Anticoagulants: Phenobarbital lowers the plasma amounts of dicumarol (name Earlier made use of: bishydroxycoumarin) and triggers a lessen in anticoagulant action as calculated via the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing enhanced metabolism and diminished anticoagulant reaction of oral anticoagulants (e.Cortiā¦ Read More